Histology Guide

virtual histology laboratory

Chapter 4 - Muscle Tissue

Muscle cells (myofibers) synthesize and maintain the contractile function of connective tissue. Three types of muscle are recognized based on their distinctive structural and functional features: skeletal, cardiac muscle and smooth muscle.

Skeletal Muscle

Skeletal muscle is composed of long, multinuclear cells with the nuclei located at the periphery of the cell. The cells are straited because of the parallel arrangement of contractile filaments appear as an alternating series of transverse bands.

EM 222 Skeletal Muscle

Cardiac Muscle

Cardiac muscle is composed of branched, mononuclear cells (occasionally bi-nucleate) with the nuclei located in the center of the cell. The cells show the same striations as skeletal muscle.

EM 137 Cardiac Muscle

EM 122 Cardiac Muscle

EM 133 Cardiac Muscle

Smooth Muscle

Smooth muscle contains the same contractile proteins as skeletal and cardiac muscle, but the less ordered array of contractile filaments does not produce striations.

EM 132 Smooth Muscle Cell

EM 121 Smooth Muscle Cells

EM 126 Smooth Muscle