Histology Guide

virtual histology laboratory

Chapter 5 - Cartilage and Bone

Cartilage and bone are a specialized connective tissues for support. Cartilage occurs where flexibility is required, while bone resists deformation.


Three types of cartiage can be distinguished based on the relative amount of fibers and ground substance: hyaline cartilage, elastic cartilage and fibrocartilage.

Hyaline Cartilage

Hyaline cartilage contains abundant ground substance with fibers of type II collagen.

EM 147 Cartilage

EM 149 Chondrocyte


Bone is hard and rigid. It is mineralized and forms the supportive framework for the body. Morphologically, bone is organized into two types: compact bone and spongey (cancellous or trabecular) bone.

EM 215 Tibia

EM 217 Osteon

EM 218 Osteocyte